Methyl iodide → HCID 13107028, compound

HRID 980337Notes

Reaction equation

HRID 980337 reaction equation
[C:1]([C:5]1[CH:6]=[C:7]([C:16]2[NH:17][C:18](=[S:22])[NH:19][C:20]=2[CH3:21])[CH:8]=[C:9]([C:12]([CH3:15])([CH3:14])[CH3:13])[C:10]=1[OH:11])([CH3:4])([CH3:3])[CH3:2].[C:23](=O)([O-])[O-].[K+].[K+].CI>CC(C)=O>[C:1]([C:5]1[CH:6]=[C:7]([C:16]2[N:17]=[C:18]([S:22][CH3:23])[NH:19][C:20]=2[CH3:21])[CH:8]=[C:9]([C:12]([CH3:14])([CH3:15])[CH3:13])[C:10]=1[OH:11])([CH3:2])([CH3:3])[CH3:4]

Participants

5

Reactant 3

HCID 6328Methyl iodideHCID 11430Potassium CarbonateHCID 13107025HCID 13107025, compound

Product 1

HCID 13107028HCID 13107028, compoundYield 29.9%

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

By following the same procedure as in Example 10 using 0.32 g of 4-(3,5-di-tert-butyl-4-hydroxyphenyl)-5-methyl-2-thioxo-4-imidazoline, 10 ml of dry acetone, 0.15 g of potassium carbonate, and 0.15 g of methyl iodide and recrystallizing the product from cyclohexane, 0.1 g of 4-(3,5-di-tert-butyl-4-hydroxyphenyl)-5-methyl-2-methylthioimidazole was obtained.

Workup

  1. customrecrystallizing the product from cyclohexane

Sources & evidence

ORD record
ord-c0a4b4458b494be78d029759bb692b80
Source dataset
uspto-grants-1987_01
Patent number
US04636516

Reaction notes

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