HCID 13107038, compound → 2,6-Di-tert-butyl-4-(5-ethyl-1H-imidazol-4-yl)phenol

HRID 980348Notes

Reaction equation

HRID 980348 reaction equation
[C:1]([C:5]1[CH:6]=[C:7]([C:16]2[NH:17][C:18](=S)[NH:19][C:20]=2[CH2:21][CH3:22])[CH:8]=[C:9]([C:12]([CH3:15])([CH3:14])[CH3:13])[C:10]=1[OH:11])([CH3:4])([CH3:3])[CH3:2]>[Ni].C(O)C>[C:12]([C:9]1[CH:8]=[C:7]([C:16]2[N:17]=[CH:18][NH:19][C:20]=2[CH2:21][CH3:22])[CH:6]=[C:5]([C:1]([CH3:2])([CH3:3])[CH3:4])[C:10]=1[OH:11])([CH3:13])([CH3:14])[CH3:15]

Participants

4

Reactant 1

HCID 13107038HCID 13107038, compound

Product 1

HCID 137543182,6-Di-tert-butyl-4-(5-ethyl-1H-imidazol-4-yl)phenolYield 49.8%

Reagents, catalysts & solvents 2

HCID 935NickelCatalystHCID 702EthanolSolvent

Procedure

By following the same procedure as in Example 17 using 2 g of 4-(3,5-di-tert-butyl-4-hydroxyphenyl)-5-ethyl-2-thioxo-4-imidazoline, 50 ml of absolute ethanol, and 1 g of a Raney nickel catalyst and recrystallizing the reaction product from toluene, 0.9 g of 4-(3,5-di-tert-butyl-4-hydroxyphenyl)-5-ethylimidazole was obtained.

Workup

  1. customrecrystallizing the reaction product from toluene

Sources & evidence

ORD record
ord-8cca0cf512e84647815724ea5ec268b1
Source dataset
uspto-grants-1987_01
Patent number
US04636516

Reaction notes

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