反应详情

To 15 ml of ice-cooled acetic acid solution of 25% hydrobromic acid was added 1.14 g of compound (37) and the reaction was maintained for 3 hours at room temperature. The reaction mixture thus obtained was added to 150 ml of desiccated ether, the precipitates thus formed were quickly collected by filtration and dried overnight in a desiccator at reduced pressure to provide 1.53 g of L-histidyl-N-cyclohexyl-L-prolinamide.2-hydrobromide.

1. customThe reaction mixture thus obtained
2. customthe precipitates thus
3. customformed
4. filtrationwere quickly collected by filtration
5. customdried overnight in a desiccator at reduced pressure