Methyl iodide → HCID 86741228, compound

Participants

Reaction Steps

4.0 g of 2-sulfonylmethyl-6-methylpyrazine sodium salt (2900) was added to a solution of 15 ml methyl iodide/30 ml methanol and the mixture refluxed for 4 days. It was then cooled and filtered. The solid was chromatographed (Biogel P-2/water) and freeze-dried to give 3.4 g of product (3000). It was recrystallized from propanol/water, m.p.>280° (dec.). UV H2O max: 288 (3.92).

Provenance & Evidence