Methyl iodide → HCID 86741230, compound

Participants

Reaction Steps

2.0 g of 2-sulfonylmethyl-5-methylpyrazine sodium salt (3100) was added to a solution of 15 ml methyl iodide/25 ml methanol and refluxed for 5 days. The mixture was then cooled and filtered. The solid was purified by gel permeation chromatography (Biogel P-2/water) and freeze-dried to give 1.6 g of product (3200). It was recrystallized from propanol/water, m.p.>350° (dec.) UV H2O max: 213 (3.91), 293 (3.87).

Provenance & Evidence