HCID 20221618, compound → HCID 20221583, compound

HRID 980483Notes

Reaction equation

HRID 980483 reaction equation
[I-:1].[CH3:2][N+:3]1[CH:8]=[CH:7][N:6]=[C:5]([CH2:9][CH2:10][C:11]([O:13]C)=[O:12])[CH:4]=1>Cl>[I-:1].[CH3:2][N+:3]1[CH:8]=[CH:7][N:6]=[C:5]([CH2:9][CH2:10][C:11]([OH:13])=[O:12])[CH:4]=1

Participants

3

Reactant 1

HCID 20221618HCID 20221618, compound

Product 1

HCID 20221583HCID 20221583, compoundYield 57.6%

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

1.0 g of 1-methyl-3-(2-carbomethoxyethyl)pyrazinium iodide was dissolved in 30 ml of 2N HCl and refluxed overnight. It was then concentrated, taken up in 100 ml of water and washed with methylene chloride. Concentration of the aqueous solution gave 0.55 g of 1-methyl-3-(2-carboxyethyl)pyrazinium iodide (3900) as an amorphous solid. UV H2O max: 226 (4.12), 281 (3.85).

Workup

  1. temperaturerefluxed overnight
  2. concentrationIt was then concentrated
  3. washwashed with methylene chloride

Sources & evidence

ORD record
ord-abf56a911e52440b89dbc6598c18a7cf
Source dataset
uspto-grants-1987_01
Patent number
US04638005

Reaction notes

Loading…