Sodium → HCID 20220430, compound

HRID 980779Notes

Reaction equation

HRID 980779 reaction equation
[C:1]([C:3]1[CH:28]=[CH:27][C:6]([CH2:7][S:8][C:9]2[CH:13]=[C:12]([CH:14]3[CH2:19][CH2:18][CH:17]([CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])[CH2:16][CH2:15]3)[S:11][C:10]=2[CH:25]=O)=[CH:5][CH:4]=1)#[N:2].[Na]>C(O)C>[C:1]([C:3]1[CH:28]=[CH:27][C:6]([C:7]2[S:8][C:9]3[CH:13]=[C:12]([CH:14]4[CH2:19][CH2:18][CH:17]([CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])[CH2:16][CH2:15]4)[S:11][C:10]=3[CH:25]=2)=[CH:5][CH:4]=1)#[N:2]

Participants

4

Reactant 2

HCID 5360545SodiumHCID 20220558HCID 20220558, compound

Product 1

HCID 20220430HCID 20220430, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

A solution of 4.6 g of 3-p-cyanobenzylmercapto-2-formyl-5-(4-pentylcyclohexyl)-thiophene in 25 ml of ethanol is added dropwise, at room temperature and in the course of 5 minutes, to an alcoholate solution prepared from 1.9 g of sodium and 60 ml of ethanol, and the mixture is then boiled for 5 hours. The usual working-up procedure gives 2-p-cyanophenyl-5-(4-pentylcyclohexyl)-thieno[3,2-b]thiophene.

Sources & evidence

ORD record
ord-30478306a0c648b79532a00896145df2
Source dataset
uspto-grants-1987_01
Patent number
US04639328

Reaction notes

Loading…