Diethyl Ether → {1-[3-(aminocarbonyl)phenyl]-5-chloro-4-[(2,4-difluorobenzyl)oxy]-6-oxo-1,6-dihydropyridin-2-yl}methyl Acetate

HRID 98079Notes

Reaction equation

HRID 98079 reaction equation
[C:1]([CH3:2])(=[O:3])[O:4][CH2:5][c:6]1[n:7](-[c:23]2[cH:24][c:25]([C:29](=[O:30])[NH2:31])[cH:26][cH:27][cH:28]2)[c:8](=[O:22])[cH:9][c:10]([O:12][CH2:13][c:14]2[c:15]([F:21])[cH:16][c:17]([F:20])[cH:18][cH:19]2)[cH:11]1.[CH3:49][CH2:50][O:51][CH2:52][CH3:53].[Cl:32][N:33]1[C:34](=[O:35])[CH2:36][CH2:37][C:38]1=[O:39].[Cl:46][CH2:47][Cl:48].[OH:40][C:41]([CH:42]([Cl:43])[Cl:44])=[O:45]>>[C:1]([CH3:2])(=[O:3])[O:4][CH2:5][c:6]1[n:7](-[c:23]2[cH:24][c:25]([C:29](=[O:30])[NH2:31])[cH:26][cH:27][cH:28]2)[c:8](=[O:22])[c:9]([Cl:32])[c:10]([O:12][CH2:13][c:14]2[c:15]([F:21])[cH:16][c:17]([F:20])[cH:18][cH:19]2)[cH:11]1

Participants

6

Reactant 5

HCID 3283Diethyl EtherHCID 6344DichloromethaneHCID 6597Dichloroacetic AcidHCID 31398ChlorosuccinimideHCID 22050389HCID 22050389, compound

Product 1

HCID 22050051{1-[3-(aminocarbonyl)phenyl]-5-chloro-4-[(2,4-difluorobenzyl)oxy]-6-oxo-1,6-dihydropyridin-2-yl}methyl Acetate

Sources & evidence

ORD record
ord-c0472458f1804fecbe1223dea1c68fdf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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