Piperidine → Cholesterol 5alpha,6alpha-Epoxide Piperidine

HRID 980791Notes

Reaction equation

HRID 980791 reaction equation
[CH3:1][C@@H:2]([C@@H:9]1[C@@:13]2([CH3:29])[CH2:14][CH2:15][C@@H:16]3[C@@:21]4([CH3:27])[CH2:22][CH2:23][C@H:24]([OH:26])[CH2:25][C@:20]54[O:28][C@H:19]5[CH2:18][C@H:17]3[C@@H:12]2[CH2:11][CH2:10]1)[CH2:3][CH2:4][CH2:5][CH:6]([CH3:8])[CH3:7].[NH:30]1[CH2:35][CH2:34][CH2:33][CH2:32][CH2:31]1>>[CH3:1][C@@H:2]([C@@H:9]1[C@@:13]2([CH3:29])[CH2:14][CH2:15][C@@H:16]3[C@@:21]4([CH3:27])[CH2:22][CH2:23][C@H:24]([OH:26])[CH2:25][C@:20]54[O:28][C@H:19]5[CH2:18][C@H:17]3[C@@H:12]2[CH2:11][CH2:10]1)[CH2:3][CH2:4][CH2:5][CH:6]([CH3:7])[CH3:8].[NH:30]1[CH2:35][CH2:34][CH2:33][CH2:32][CH2:31]1

Participants

3

Reactant 2

HCID 8082PiperidineHCID 2270375alpha,6alpha-Epoxycholesterol

Product 1

HCID 131715040Cholesterol 5alpha,6alpha-Epoxide Piperidine

Procedure

Following the procedure of Example 29 in either aqueous or aqueous-alcoholic solution the interaction of cholesterol 5α,6α-epoxide and piperidine results in the desired product. ##STR16##

Sources & evidence

ORD record
ord-0a6601a21809428bafee38cda15524fe
Source dataset
uspto-grants-1987_01
Patent number
US04639420

Reaction notes

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