2-Thiophenecarbonyl chloride → HCID 13228911, compound

HRID 980818Notes

Reaction equation

HRID 980818 reaction equation
[C:1]1([C:6](Cl)=[O:7])[S:5][CH:4]=[CH:3][CH:2]=1.[NH2:9][C:10]1[CH:15]=[CH:14][C:13]([C:16]2[CH:17]([CH3:23])[CH2:18][C:19](=[O:22])[NH:20][N:21]=2)=[CH:12][CH:11]=1>C1C=CC=CC=1>[C:1]1([C:6]([NH:9][C:10]2[CH:15]=[CH:14][C:13]([C:16]3[CH:17]([CH3:23])[CH2:18][C:19](=[O:22])[NH:20][N:21]=3)=[CH:12][CH:11]=2)=[O:7])[S:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 789282-Thiophenecarbonyl chlorideHCID 161928Ici 109,081

Product 1

HCID 13228911HCID 13228911, compoundYield 51.9%

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

A mixture of 1.1 g of 2-thenoyl chloride, 1.0 g of 6-(p-aminophenyl)-5-methyl-4,5-dihydro-3(2H)-pyridazinone and 10 ml of benzene was treated in the same manner as described in Example 1 to effect reaction whereby 800 mg of the title compound was obtained. M.P. 256°-258° C.

Workup

  1. additionwas treated in the same manner

Sources & evidence

ORD record
ord-ec37c800645942f980234c3e0c4de6af
Source dataset
uspto-grants-1987_01
Patent number
US04639451

Reaction notes

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