m-Chloroperbenzoic acid → HCID 53948062, compound

HRID 980837Notes

Reaction equation

HRID 980837 reaction equation
ClC1C=CC=C(C(OO)=[O:9])C=1.[C:12]([C:14]1[CH:29]=[CH:28][C:17]2[CH2:18][CH2:19][C:20]3[C:21]([C:26](=[O:27])[C:16]=2[CH:15]=1)=[N:22][CH:23]=[CH:24][CH:25]=3)#[N:13]>C(Cl)(Cl)Cl>[C:12]([C:14]1[CH:29]=[CH:28][C:17]2[CH2:18][CH2:19][C:20]3[C:21]([C:26](=[O:27])[C:16]=2[CH:15]=1)=[N+:22]([O-:9])[CH:23]=[CH:24][CH:25]=3)#[N:13]

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acid2×HCID 20221006HCID 20221006, compound

Product 1

HCID 53948062HCID 53948062, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

In a manner similar to that described in Example II, 1.19 grams (0.0055 mole) of m-chloroperbenzoic acid is added to a solution of 1.29 grams (0.005 mole) of 9-cyano-5,6-dihydrobenzo[5,6]cyclohepta[1,2-b]pyridin-11-one in 20 milliliters of chloroform and the resulting mixture stirred at ambient temperature for several days with an addition of an about 0.5 gram portion of m-chloroperbenzoic acid after the first 24 hours. At the end of this period the mixture is washed, dried and evaporated to obtain a 9-cyano-5,6-dihydrobenzo[5,6]cyclohepta[1,2-b]-pyridin-11-one N-oxide intermediate as residue.

Workup

  1. washAt the end of this period the mixture is washed
  2. customdried
  3. customevaporated

Sources & evidence

ORD record
ord-ae96edc3a436480590b2d03ba282b7da
Source dataset
uspto-grants-1987_01
Patent number
US04639457

Reaction notes

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