Hydroxyacetonitrile → (Dodecylamino)acetonitrile

HRID 980862Notes

Reaction equation

HRID 980862 reaction equation
O[CH2:2][C:3]#[N:4].[CH2:5]([NH2:17])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16]>CO>[CH2:5]([NH:17][CH2:2][C:3]#[N:4])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16]

Participants

4

Reactant 2

HCID 7857HydroxyacetonitrileHCID 13583Dodecylamine

Product 1

HCID 222308(Dodecylamino)acetonitrile

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

In a flask of 500 ml provided with a magnetic stirrer, 4.56 gr of hydroxyacetonitrile (0.08 mol) were mixed at room temperature with 16.3 gr of dodecylamine (0.088 mol) in 250 ml of methanol. The mixture was allowed to stand for 16 hours at room temperature and methanol was evaporated. The obtained liquid was distilled under 10-2 mm Hg. The fraction distilling between 106° and 116° crystallizes after cooling.

Workup

  1. customIn a flask of 500 ml provided with a magnetic stirrer
  2. custommethanol was evaporated
  3. distillationThe obtained liquid was distilled under 10-2 mm Hg
  4. distillationThe fraction distilling between 106° and 116°
  5. customcrystallizes
  6. temperatureafter cooling

Sources & evidence

ORD record
ord-062b5b872d41428695569fdb5abf608a
Source dataset
uspto-grants-1987_01
Patent number
US04639468

Reaction notes

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