Hydroxyacetonitrile → HCID 12878154, compound

HRID 980863Notes

Reaction equation

HRID 980863 reaction equation
O[CH2:2][C:3]#[N:4].[CH2:5]([NH2:11])[CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]>CO>[CH2:5]([NH:11][CH2:2][C:3]#[N:4])[CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]

Participants

4

Reactant 2

HCID 7857HydroxyacetonitrileHCID 8102Hexylamine

Product 1

HCID 12878154HCID 12878154, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

In a flask of 100 ml, 5.7 gr of hydroxyacetonitrile (0.1 mol) were mixed with 11 gr of hexylamine (0.11 mol) dissolved in 10 ml of MeOH. The temperature quickly raised during mixing. The solution was allowed to stand for 24 hours. The methanol was evaporated and the obtained liquid was distilled at 72° under 0.8 mm Hg.

Workup

  1. temperatureThe temperature quickly raised
  2. additionduring mixing
  3. customThe methanol was evaporated
  4. distillationthe obtained liquid was distilled at 72° under 0.8 mm Hg

Sources & evidence

ORD record
ord-9475fb1c7b9a40afae58ce4b66dfa890
Source dataset
uspto-grants-1987_01
Patent number
US04639468

Reaction notes

Loading…