Sulfuric Acid → HCID 12878147, compound

HRID 980864Notes

Reaction equation

HRID 980864 reaction equation
[CH2:1]([NH:7][CH2:8][C:9]#[N:10])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].[OH:11]S(O)(=O)=O>C(O)C>[CH2:1]([NH:7][CH2:8][C:9]([NH2:10])=[O:11])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6]

Participants

4

Reactant 2

HCID 1118Sulfuric AcidHCID 12878154HCID 12878154, compound

Product 1

HCID 12878147HCID 12878147, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Conditions

Temperature
100 °C

Procedure

11.2 gr of hexylaminoacetonitrile (0.081 mol) were dropwise added to 31 ml of H2SO4 diluted in 30 ml of ice-cooled ethanol. After the addition was completed, ethanol was evaporated and 40 ml of H2SO4 were added to the white solid as obtained. This solution was heated for 1 hour at 100° C., then cooled and dropwise added to 200 ml of ice-cooled ethanol. The white precipitate which formed was filtered and washed with 50 ml of ethanol.

Workup

  1. additionAfter the addition
  2. customethanol was evaporated
  3. addition40 ml of H2SO4 were added to the white solid
  4. customas obtained
  5. temperaturecooled
  6. customThe white precipitate which formed
  7. filtrationwas filtered
  8. washwashed with 50 ml of ethanol

Sources & evidence

ORD record
ord-a25326dfb42a45ea8bb0df6a4b6ac00e
Source dataset
uspto-grants-1987_01
Patent number
US04639468

Reaction notes

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