Methyl iodide → HCID 12878153, compound

In a flask of 100 ml, 7.9 gr (0.05 mol) of 2-(n-hexylamino)acetamide and 7.8 gr (0.055 mol) of methyl iodide were mixed in 50 ml of methanol. This solution was left for 1 month at room temperature, then evaporated. The residue was dissolved in a 1N NaOH solution until basic pH and extracted with ether. The ether phase was dried on MgSO4 and evaporated. The solid as obtained was chromatographed on a column of SiO2 by eluting with a benzene-methanol mixture (7:3). The desired product was thus obtained.

1. waitThis solution was left for 1 month at room temperature
2. customevaporated
3. dissolutionThe residue was dissolved in a 1N NaOH solution until basic pH
4. extractionextracted with ether
5. dry with materialThe ether phase was dried on MgSO4
6. customevaporated
7. customThe solid as obtained
8. customwas chromatographed on a column of SiO2
9. washby eluting with a benzene-methanol mixture (7:3)

ORD record

ord-8834e339b4294619904cce032efb5fe7

Source dataset

uspto-grants-1987_01

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US04639468