Methyl iodide → HCID 12878153, compound

Participants

Reaction Steps

In a flask of 100 ml, 7.9 gr (0.05 mol) of 2-(n-hexylamino)acetamide and 7.8 gr (0.055 mol) of methyl iodide were mixed in 50 ml of methanol. This solution was left for 1 month at room temperature, then evaporated. The residue was dissolved in a 1N NaOH solution until basic pH and extracted with ether. The ether phase was dried on MgSO4 and evaporated. The solid as obtained was chromatographed on a column of SiO2 by eluting with a benzene-methanol mixture (7:3). The desired product was thus obtained.

Provenance & Evidence