HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorosuccinimide → 8-Chloro-5,6-dimethoxy-3-methylquinazolin-2,4(1H, 3H)-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorosuccinimide | HCID 31398 | — |
| Reactant | 5,6-Dimethoxy-3-methylquinazolin-2,4(1H, 3H)-dione | HCID 13772013 | — |
| Product | 8-Chloro-5,6-dimethoxy-3-methylquinazolin-2,4(1H, 3H)-dione | HCID 54047963 | 67% |
Reaction Steps
Following the procedure employed in Example 11, treatment of 5,6-dimethoxy-3-methylquinazolin-2,4(1H, 3H)-dione 1/4 hydrate with N-chlorosuccinimide gives the title compound after isopropanol crystallization in 67% yield, mp 224°-227° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04639518 |
| Source dataset | uspto-grants-1987_01 |
| ORD ID | ord-8d6f30a41a23470daf16b507adfdac77 |
| Source note | uspto-grants-1987_01 |