Chlorosuccinimide → HCID 13772051, compound

HRID 980885Notes

Reaction equation

HRID 980885 reaction equation
Br[C:2]1[CH:3]=[C:4]2[O:16][CH2:15][O:14][C:5]2=[C:6]([C:12]=1[NH2:13])[C:7]([O:9][CH2:10][CH3:11])=[O:8].[Cl:17]N1C(=O)CCC1=O>>[CH2:10]([O:9][C:7](=[O:8])[C:6]1[C:12]([NH2:13])=[C:2]([Cl:17])[CH:3]=[C:4]2[O:16][CH2:15][O:14][C:5]=12)[CH3:11]

Participants

3

Reactant 2

HCID 31398ChlorosuccinimideHCID 13772050HCID 13772050, compound

Product 1

HCID 13772051HCID 13772051, compoundYield 75%

Procedure

Following the procedure employed in Example 27, treatment of ethyl 5-bromo-2,3-methylenedioxy-6-aminobenzoate with N-chlorosuccinimide instead of N-bromosuccinimide, gave the title compound in 75% yield after silica gel chromatography, mp 77°-78° C.

Sources & evidence

ORD record
ord-b1c589a28b414a30a24a15d715e509cc
Source dataset
uspto-grants-1987_01
Patent number
US04639518

Reaction notes

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