Benzylamine → HCID 13361996, compound

HRID 980944Notes

Reaction equation

HRID 980944 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[CH2:13][C:12](=[O:14])[O:11][C:9]2=[O:10])=[CH:4][CH:3]=1.[CH3:15][O:16][C:17]1[CH:18]=[C:19]([CH:22]=[CH:23][CH:24]=1)[CH:20]=O.[CH2:25]([NH2:32])[C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1>C1(C)C(C)=CC=CC=1>[CH2:25]([N:32]1[CH:20]([C:19]2[CH:22]=[CH:23][CH:24]=[C:17]([O:16][CH3:15])[CH:18]=2)[C:8]([C:5]2[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][CH:4]=2)([C:9]([OH:11])=[O:10])[CH2:13][C:12]1=[O:14])[C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1

Participants

5

Reactant 3

HCID 7504BenzylamineHCID 115693-MethoxybenzaldehydeHCID 2894693-(4-chlorophenyl)dihydrofuran-2,5-dione

Product 1

HCID 13361996HCID 13361996, compound

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Conditions

Temperature
0 °C

Procedure

6.3 g (0.03 mole) of (4-chlorophenyl)-succinic anhydride and 6.75 g (0.03 mole) of Schiff base, prepared from 3-methoxybenzaldehyde and benzylamine, according to the general procedure, are refluxed at 140° C. in 90 ml of xylene for 12 hr. After cooling to 0° C. the solid is collected, washed with xylene and ether: 9.15 g (70%) of title compound mp 76°-8° C.

Workup

  1. customis collected
  2. washwashed with xylene and ether

Sources & evidence

ORD record
ord-d91eb2fb69f643828d7de71d8c88da81
Source dataset
uspto-grants-1987_01
Patent number
US04639529

Reaction notes

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