Potassium Carbonate → HCID 15069997, compound

HRID 981085Notes

Reaction equation

HRID 981085 reaction equation
[CH3:1][N:2]1[O:9][CH2:8][CH:7]2[CH:3]1[CH2:4][N:5](C(OCC)=O)[CH2:6]2.C(=O)([O-])[O-].[K+].[K+]>O>[CH3:1][N:2]1[O:9][CH2:8][CH:7]2[CH:3]1[CH2:4][NH:5][CH2:6]2

Participants

4

Reactant 2

HCID 11430Potassium CarbonateHCID 15069996HCID 15069996, compound

Product 1

HCID 15069997HCID 15069997, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

13 g (65 mmol) of ethyl 2-methyl-3-oxa-2,7-diazabicyclo[3.3.0]octane-7-carboxylate are heated under reflux in 300 ml of water with 41 g of Ba(OH)2.8H2O overnight. Potassium carbonate is added, the barium carbonate which has precipitated out is filtered off with suction and the filtrate is extracted ten times with 100 ml of chloroform each time. The extract is dried over potassium carbonate and concentrated and the residue is distilled.

Workup

  1. customthe barium carbonate which has precipitated out
  2. filtrationis filtered off with suction
  3. extractionthe filtrate is extracted ten times with 100 ml of chloroform each time
  4. dry with materialThe extract is dried over potassium carbonate
  5. concentrationconcentrated
  6. distillationthe residue is distilled

Sources & evidence

ORD record
ord-1cd424f1b1fc4ca3ad6e526726fa1146
Source dataset
uspto-grants-1991_02
Patent number
US04990517

Reaction notes

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