Potassium Carbonate → 2,4-Dimethyl-3-oxa-2,7-diazabicyclo[3.3.0]octane

HRID 981118Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 981118
[CH3:1][N:2]1[O:9][CH:8]([CH3:10])[CH:7]2[CH:3]1[CH2:4][N:5](C(OCC)=O)[CH2:6]2.C([O-])([O-])=O.[K+].[K+]>O>[CH3:1][N:2]1[O:9][CH:8]([CH3:10])[CH:7]2[CH:3]1[CH2:4][NH:5][CH2:6]2

Komponenten

4

Edukt 2

HCID 11430Potassium CarbonateHCID 15070019Ethyl 2,4-dimethyl-3-oxa-2,7-diazabicyclo[3.3.0]octane-7-carboxylate

Produkt 1

HCID 150700202,4-Dimethyl-3-oxa-2,7-diazabicyclo[3.3.0]octane

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

13.2 g (61.6 mmol) of ethyl 2,4-dimethyl-3-oxa-2,7diazabicyclo[3.3.0]octane-7-carboxylate are heated under reflux with 39 g of Ba(OH)2.8H2O in 200 ml of water overnight. K2CO3 is added, the BaCO3 is filtered off with suction and the filtrate is extracted several times with CHCl3. The extract is dried over K2CO3 and concentrated and the residue is distilled.

Aufarbeitung

  1. filtrationthe BaCO3 is filtered off with suction
  2. extractionthe filtrate is extracted several times with CHCl3
  3. dry with materialThe extract is dried over K2CO3
  4. concentrationconcentrated
  5. distillationthe residue is distilled

Quellen und Nachweise

ORD-Eintrag
ord-4370e0ae151542fdb29dcf7617c9f1ee
Quelldatensatz
uspto-grants-1991_02
Patentnummer
US04990517

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