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HRID981361

反应详情

EQUATION

反应方程式

HRID 981361 的结构方程式

REACTANTS

反应物

2
结构：O=S(Cl)Cl
HCID24386

Thionyl chloride

Cl2OS

结构：O=C(O)c1cc(F)c(Cl)c([N+](=O)[O-])c1Cl
HCID2734259

2,4-Dichloro-5-fluoro-3-nitrobenzoic acid

C7H2Cl2FNO4

PRODUCTS

生成物

1
结构：O=C(Cl)c1cc(F)c(Cl)c([N+](=O)[O-])c1Cl
HCID11818130

Benzoyl chloride, 2,4-dichloro-5-fluoro-3-nitro-

C7HCl3FNO3

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
催化剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

254 g (1 mol) of 2,4-dichloro-5-fluoro-3-nitro-benzoic acid are refluxed in 700 ml of thionyl chloride with addition of 3 drops of dimethylformamide until the gas evolution ceases. Excess thionyl chloride is removed by distillation, and the residue is fractionated in vacuo.

WORKUP

后处理

  1. customExcess thionyl chloride is removed by distillation