HuagongsheHuagongshe Chemistry Print Report · For research reference only
Malic Acid → 1-benzyl-3-hydroxy-pyrrolidine-2,5-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Malic Acid | HCID 525 | — |
| Reactant | Benzylamine | HCID 7504 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-benzyl-3-hydroxy-pyrrolidine-2,5-dione | HCID 4189900 | — |
Reaction Steps
Heating malic acid with benzylamine in ethanol at 170° C. to give N-benzyl-3-hydroxysuccinimide and reducing with lithium aluminum hydride to give N-benzyl-3-pyrrolidinol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04990683 |
| Source dataset | uspto-grants-1991_02 |
| ORD ID | ord-40ee71678b4f4d0582cf0e37257b49a2 |
| Source note | uspto-grants-1991_02 |