1-Methylpiperazine → HCID 18643653, compound

HRID 981393Notes

Reaction equation

HRID 981393 reaction equation
[C:1]([O:5][C:6]([NH:8][C@H:9]([C:15]([OH:17])=O)[CH2:10][CH2:11][C:12](=[O:14])[NH2:13])=[O:7])([CH3:4])([CH3:3])[CH3:2].[CH3:18][N:19]1[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]1>>[C:1]([O:5][C:6]([NH:8][C@H:9]([C:15]([N:22]1[CH2:23][CH2:24][N:19]([CH3:18])[CH2:20][CH2:21]1)=[O:17])[CH2:10][CH2:11][C:12](=[O:14])[NH2:13])=[O:7])([CH3:2])([CH3:3])[CH3:4]

Participants

3

Reactant 2

HCID 531671-MethylpiperazineHCID 83687L-Glutamine, N2-((1,1-dimethylethoxy)carbonyl)-

Product 1

HCID 18643653HCID 18643653, compound

Procedure

In the same manner as in Reference Example 2, N-tert-butoxycarbonyl-L-glutamine and 1-methylpiperazine were condensed to obtain a crystal of 1-(N-tert-butoxycarbonyl-L-glutaminyl)-4-methylpiperazine (7.0 g).

Workup

  1. customcondensed

Sources & evidence

ORD record
ord-c664d0860c164997af2c4642d70f9b30
Source dataset
uspto-grants-1991_02
Patent number
US04990614

Reaction notes

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