HCID 18643597, compound → HCID 18643590, compound

Participants

Reaction Steps

10% Palladium-carbon (120 mg) was added to an ethanolic solution (20 ml) of 1-(2,4-dibenzyloxybenzoyl-L-glutaminyl)-4-phenylpiperazine (364 mg) and catalytic reduction was carried out for 6 hours at room temperature and under atmospheric pressure in hydrogen stream. Thereafter, treatments were effected in the same manner as in Example 5 (ii) to obtain powdery 1-(2,4-dihydroxybenzoyl-L-glutaminyl)-4-phenylpiperazine (169 mg).

Provenance & Evidence