HCID 14989171, compound → HCID 14989172, compound

HRID 981603Notes

Reaction equation

HRID 981603 reaction equation
C1(C[O:8][C:9]2[CH:21]=[CH:20][C:12]([C:13]([O:15][CH2:16][CH:17]3[CH2:19][CH2:18]3)=[O:14])=[CH:11][CH:10]=2)C=CC=CC=1.[H][H]>[Pd].CC(O)C>[OH:8][C:9]1[CH:10]=[CH:11][C:12]([C:13]([O:15][CH2:16][CH:17]2[CH2:19][CH2:18]2)=[O:14])=[CH:20][CH:21]=1

Participants

5

Reactant 2

HCID 14989171HCID 14989171, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 14989172HCID 14989172, compoundYield 100%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 3776IsopropanolSolvent

Procedure

A mixture of 14 parts of (cyclopropylmethyl) 4-(phenylmethoxy)benzoate and 200 parts of 2-propanol was hydrogenated at normal pressure and at room temperature with 2 parts of palladium-on-charcoal catalyst 10%. After the calculated amount of hydrogen was taken up, the catalyst was filtered off and the filtrate was evaporated, yielding 8.1 parts (100%) of (cyclopropylmethyl) 4-hydroxybenzoate as a residue (int. 4).

Workup

  1. filtrationthe catalyst was filtered off
  2. customthe filtrate was evaporated

Sources & evidence

ORD record
ord-cb31ef223d5e4f11b52f603829026ab7
Source dataset
uspto-grants-1991_02
Patent number
US04992433

Reaction notes

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