Carbon Dioxide → HCID 20070565, compound

HRID 981716Notes

Reaction equation

HRID 981716 reaction equation
[CH2:1]([S:8][CH2:9][CH2:10][C:11](=[O:23])[CH:12](C(OC(C)(C)C)=O)[C:13](=[O:15])[CH3:14])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C1(C)C=CC(S(O)(=O)=O)=CC=1.C(=O)=O>C(OCC)C>[CH2:1]([S:8][CH2:9][CH2:10][C:11](=[O:23])[CH2:12][C:13](=[O:15])[CH3:14])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 280Carbon DioxideHCID 6101p-Toluenesulfonic acidHCID 20070567HCID 20070567, compound

Product 1

HCID 20070565HCID 20070565, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

101 g (0.3 mol) of 1-benzylthio-4-tert-butoxycarbonyl-3,5-hexanedione (see Example 1) and 1.0 g of p-toluenesulfonic acid are heated at 70°-75° C. for 225 minutes in a 250 ml flask equipped with a stirrer, a thermometer, a reflux condenser and a bubble counter until the evolution of gas (CO2) is complete. 100 ml of diethyl ether are added and the mixture is washed first with 50 ml of bicarbonate and then with 100 ml of water and is subsequently concentrated and fractionated.

Workup

  1. customequipped with a stirrer
  2. washthe mixture is washed first with 50 ml of bicarbonate
  3. concentrationwith 100 ml of water and is subsequently concentrated

Sources & evidence

ORD record
ord-964d04b89bac4db99b633cfe6f8312a7
Source dataset
uspto-grants-1991_02
Patent number
US04992504

Reaction notes

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