HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,8-Diazabicyclo(5.4.0)undec-7-ene → HCID 15085937, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| Reactant | 1-Ethyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | HCID 9835179 | — |
| Reactant | 6,8-Diazabicyclo[3.2.2]nonane 2hcl | HCID 70377082 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 15085937 | HCID 15085937 | — |
Reaction Steps
A solution of 0.81 g (3.0 mmol) of -ethyl-6, 7, 8-trifluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, 0.66 g (3.3 mmol) of 6,8-diazabicyclo[3.2.2]nonane, dihydrochloride, 1.35 ml (9.0 mmol) of 1,8-diazabicyclo[5.4.0]undec-7-ene and 20 ml of acetonitrile was heated under reflux for 3 hr. After cooling to room temperature the solid was collected by filtration to give 0.52 g {of the title compound, mp 245°-250° .
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04992546 |
| Source dataset | uspto-grants-1991_02 |
| ORD ID | ord-0ce0c39b89dc4d7f98fc26dff2fbbc00 |
| Source note | uspto-grants-1991_02 |