HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methane → 2-(beta-Hydroxypropyl)amino-6-(beta-hydroxypropyl)aminonitrobenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methane | HCID 297 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-Chloro-2-(beta-hydroxypropyl)amino-6-(beta-hydroxypropyl)aminonitrobenzene | HCID 20071092 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Formic Acid | HCID 284 | — |
| Product | 2-(beta-Hydroxypropyl)amino-6-(beta-hydroxypropyl)aminonitrobenzene | HCID 20071077 | — |
Reaction Steps
340 mg of palladium at a concentration of 10% on active charcoal are added to 0.07 mole (21.3 g) of 4-chloro-2-(β-hydroxypropyl)amino-6-(β-hydroxypropyl)aminonitrobenzene in 30 ml of 96° ethanol and 29.2 ml of triethylamine, after which 5.8 ml of formic acid are run in dropwise.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04992586 |
| Source dataset | uspto-grants-1991_02 |
| ORD ID | ord-307eda3cdeb5446f830b85ccd30ab4a2 |
| Source note | uspto-grants-1991_02 |