HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 3-(2-methoxyphenyl)propanoate → 5-[3-(Ethoxycarbonyl)benzoyl]-2-methoxybenzenepropanoic acid, ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 3-(2-methoxyphenyl)propanoate | HCID 578401 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Reactant | Isophthalic acid monoethyl ester monochloride | HCID 86744615 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 5-[3-(Ethoxycarbonyl)benzoyl]-2-methoxybenzenepropanoic acid, ethyl ester | HCID 14739655 | 104.6% |
Reaction Steps
Following the procedure of Example 1, 30.6 g of isophthalic acid monoethyl ester monochloride and 30 g of ethyl 2-methoxybenzene propanoate were treated with 57 g of aluminum chloride in dichloromethane to provide 53.6 g of the desired title product, as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04992576 |
| Source dataset | uspto-grants-1991_02 |
| ORD ID | ord-9fa552aaa55947f6bfda18594facac40 |
| Source note | uspto-grants-1991_02 |