Glycolic Acid → HCID 131716801, compound

Participants

Reaction Conditions

Reaction Steps

A flame dried, 250 ml, round bottom single neck flask is charged with 102.73 g (0.9 mole) of ε-caprolactone, 5.80 g (0.05 mole) of glycolide, 7.61 g (0.10 mole) of glycolic acid, and 0.121 milliliters of stannous octoate (0.33 molar in toluene). The flask is fitted with a flame dried mechanical stirrer. The reactor is purged with nitrogen three times before venting with nitrogen. The reaction mixture is heated to 160° C. and maintained at this temperature for 24 hours. The copolymer is isolated, characterized, and tested for absorption. The results are reported in Table 1.

Provenance & Evidence