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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 982210Generated: October 30, 2026

Acetic Acid → 4'-Hydroxyacetophenone

https://huagongshe.com/reaction/982210

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantPhenolHCID 996—
Product4'-HydroxyacetophenoneHCID 7469—

Reaction Steps

The same type of reaction is disclosed in U.S. Pat. Nos. 4,560,789 and 4,568,763 in which phenol is reacted with acetic acid in HF to form 4-hydroxyacetophenone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04994623
Source datasetuspto-grants-1991_02
ORD IDord-0814dc7300af4c8cae3555c2e7df83d4
Source noteuspto-grants-1991_02