HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl isocyanate → Ethyl 4-(3-ethylureido)-2-[p-(4-phenylbutoxy)benzamido]phenoxyacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl isocyanate | HCID 8022 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-Amino-2-[p-(4-phenylbutoxy)benzamido]phenoxyacetate hydrochloride | HCID 67944477 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Ethyl 4-(3-ethylureido)-2-[p-(4-phenylbutoxy)benzamido]phenoxyacetate | HCID 15106501 | — |
Reaction Steps
To a mixture of 200 mg of ethyl (4-amino-2-[p-(4-phenylbutoxy)benzamido]phenoxyacetate hydrochloride, 40.5 mg of triethylamine and 5 mg of methylene chloride was added 30 mg of ethyl isocyanate followed by stirring at room temperature overnight. The reaction mixture was treated in a manner similar to Example 68 to obtain 130 mg of ethyl 4-(3-ethylureido)-2-[p-(4-phenylbutoxy)benzamido]phenoxyacetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04994479 |
| Source dataset | uspto-grants-1991_02 |
| ORD ID | ord-644d20d173484364bbff9de7b8d5261b |
| Source note | uspto-grants-1991_02 |