HCID 178497769, compound → HCID 178497768, compound

Participants

Reaction Steps

A mixture of 1.0 g of methyl 4-(4-hydroxy-5-pivaloyloxymethyl-6-methylpyrrolo[2,3-d]pyrimidin-3-ylethynyl)benzoate in 250 mL of 50% methanol in methylyne chloride and 0.8 g of 3% palladium-on-carbon is hydrogenated under reduced pressure. The solid is collected and there is obtained methyl 4-[2-(4-hydroxy-6-methylpyrrolo[2,3-d]pyrimidin-3-yl)ethyl]benzoate.

Provenance & Evidence