反应详情

43.4 g (0.142 mol) of 1-acetyl-4-(4-methylsulfonylaminobenzoyl)piperidine was suspended in 1 l of 3N hydrochloric acid and the suspension was stirred under reflux for 3 h. After completion of the reaction, the liquid reaction mixture was cooled and white crystals thus formed were filtered, washed with water and dried to obtain 37.8 g (yield: 84%) of the intended compound.

1. temperatureunder reflux for 3 h
2. customAfter completion of the reaction
3. customthe liquid reaction mixture
4. temperaturewas cooled
5. customwhite crystals thus formed
6. filtrationwere filtered
7. washwashed with water
8. customdried