6-(Pyrimidin-5-YL)hex-5-YN-1-OL → 6-(Pyrimidin-5-yl)hexan-1-ol

Participants

Reaction Steps

A solution of 6-(5-pyrimidinyl)-5-hexynol (3.52 g) in ethanol (20 ml) was added to a pre-hydrogenated suspension of 10% palladium on carbon (1 g) in ethanol (130 ml) and hydrogenated at room temperature and pressure. The mixture was filtered through hyflo and the filtrate evaporated in vacuo to give the title compound as a pale yellow oil (3.38 g).

Provenance & Evidence