Sodium Hydroxide → HCID 14651083, compound

Participants

Reaction Steps

A 1N NaOH solution (30 ml, 30 mmoles) was added to a solution of the 3,5-dihydroxyester prepared in Step 9 (9.70 g, 24 mmoles) and 60 ml of ethanol. After stirring for 10 minutes, the ethanol was evaporated in vacuo. The residue was redissolved in H2O and extracted twice with ether. The aqueous layer was acidified with 33 ml of 1N HCl and extracted twice with H2CCl2. The H2CCl2 was removed in vacuo.

Provenance & Evidence