Potassium Carbonate → HCID 15718069, compound

HRID 982450Notes

Reaction equation

[CH2:1]([O:3][C:4](=[O:22])[C:5]1[CH:10]=[CH:9][C:8]([O:11][C:12]2[CH:17]=[CH:16][C:15]([CH2:18][CH:19]=[CH2:20])=[C:14]([OH:21])[CH:13]=2)=[CH:7][CH:6]=1)[CH3:2].[CH2:23](I)[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32].C(=O)([O-])[O-].[K+].[K+]>>[CH2:1]([O:3][C:4](=[O:22])[C:5]1[CH:6]=[CH:7][C:8]([O:11][C:12]2[CH:17]=[CH:16][C:15]([CH2:18][CH:19]=[CH2:20])=[C:14]([O:21][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32])[CH:13]=2)=[CH:9][CH:10]=1)[CH3:2]

Participants

Reactant 3

HCID 11430Potassium Carbonate

HCID 163141-Iododecane

HCID 15718068HCID 15718068, compound

Product 1

HCID 15718069HCID 15718069, compoundYield 48.1%

Procedure

Following the general procedure of Example 1H above, 7.11 g of 4-[3-hydroxy-4-(2-propenyl)phenoxy]benzoic acid ethyl ester was allowed to react with 6.38 g of decyl iodide in the presence of 3.3 g of potassium carbonate to provide 5.02 g of the desired subtitle intermediate as an oil.

Sources & evidence

ORD record: ord-253325a35c874f3a9b0c2604f334d77b
Source dataset: uspto-grants-1991_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04996230

Reaction notes

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