反应详情

A mixture of 106 g (0.36 mols) of 1.2-dibromo-4.5-dimethoxy-benzene, 98 g (1.06 mols) of copper cyanide and 300 ml of dimethylformamide is brought to reflux for five hours, then the mixture is cooled and is poured into 500 ml of 30% ammonia. The residue is again mixed for 10 minutes, then is filtered and washed with water and dried. The product is extracted by ether for 24 hours by using a Soxhlet device and the solvent is evaporated. Thus, 40 g of 1.2-dicyano-4.5 dimethoxybenzene is obtained in the form of white flakes, which corresponds to a yield of 58%.

1. temperatureto reflux for five hours
2. temperaturethe mixture is cooled
3. additionThe residue is again mixed for 10 minutes
4. filtrationis filtered
5. washwashed with water
6. customdried
7. extractionThe product is extracted by ether for 24 hours
8. customthe solvent is evaporated