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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 982568Generated: October 31, 2026

HCID 54497776, compound → HCID 54511782, compound

https://huagongshe.com/reaction/982568

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 54497776HCID 54497776—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 54511782HCID 5451178298.6%

Reaction Steps

0.4 g of [N-formyl-N-benzyloxy 2(RS)-isobutyl-3-aminopropionyl]-L-leucylglycine ethyl ester in 20 ml of ethanol was hydrogenated for 0.75 hour in the presence of 5% palladium/carbon. The mixture was filtered, the filtrate was evaporated and the residue was dried in vacuo to yield 0.32 g (98%) of [N-formyl-N-hydroxy 2(RS)-isobutyl-3-aminopropionyl]-L-leucylglycine ethyl ester as a foam.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04996358
Source datasetuspto-grants-1991_02
ORD IDord-3738db60974b43a8866fb9d7bd0aa02b
Source noteuspto-grants-1991_02