Dimethylformamide dimethyl acetal → HCID 69736561, compound

Participants

Reaction Steps

A solution of 1.71 g (5 mmol) of 2-amino-4-(1-fluoro-1-methylethyl)-6-(1-cyclopropyl-4-phenyl-1-butylamino)-1,3,5-triazine and 2 ml of N,N-dimethylformamide dimethyl acetal in 30 ml of toluene is refluxed for 2 hours. All volatile constituents are subsequently carefully distilled off. This gives 1.94 g (97.5% of theory) of 2-dimethylaminomethyleneamino-4-(1-fluoro-1-methylethyl)-6-(1-cyclopropyl-4-phenyl-1-butylamino)-1,3,5-triazine as colorless oil.

Provenance & Evidence