Dichloromethane → 4-(2-Methoxyphenyl)piperidine

HRID 98265Notes

Reaction equation

HRID 98265 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][CH:11]([c:14]2[c:15]([O:20][CH3:21])[cH:16][cH:17][cH:18][cH:19]2)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[CH2:29]([Cl:30])[Cl:31].[OH:22][C:23]([C:24]([F:25])([F:26])[F:27])=[O:28]>>[NH:8]1[CH2:9][CH2:10][CH:11]([c:14]2[c:15]([O:20][CH3:21])[cH:16][cH:17][cH:18][cH:19]2)[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 22629567Tert-butyl 4-(2-methoxyphenyl)piperidine-1-carboxylate

Product 1

HCID 5447384-(2-Methoxyphenyl)piperidine

Sources & evidence

ORD record
ord-33435c37f1754cda9c6a11f0e23764d8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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