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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 983227Generated: October 31, 2026

m-Tolylacetic acid → N-[(3-methylphenyl)acetyl]alanine Iso-butyl Ester

https://huagongshe.com/reaction/983227

Reaction equation

Participants

RoleNameHCIDCharge
Reactantm-Tolylacetic acidHCID 12121—
Reactant2-methylpropyl (2S)-2-aminopropanoateHCID 13743556—
ProductN-[(3-methylphenyl)acetyl]alanine Iso-butyl EsterHCID 53803690—

Reaction Steps

Following General Procedure I′ above, and using 3-methylphenylacetic acid (Aldrich) and alanine iso-butyl ester (prepared following General Procedure J′ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06861558B2
Source datasetuspto-grants-2005_03
ORD IDord-244b076629cd443fa79edb7fd2a3ad61
Source noteuspto-grants-2005_03