Acetic Anhydride → Ethanol, 2-(ethylphenylamino)-, 1-acetate

HRID 983573Notes

Reaction equation

HRID 983573 reaction equation
[CH2:1]([N:3]([CH2:10][CH2:11][OH:12])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)[CH3:2].[C:13](OC(=O)C)(=[O:15])[CH3:14]>>[CH2:1]([N:3]([CH2:10][CH2:11][O:12][C:13](=[O:15])[CH3:14])[C:4]1[CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=1)[CH3:2]

Participants

3

Reactant 2

HCID 7918Acetic AnhydrideHCID 623382-(N-ethylanilino)ethanol

Product 1

HCID 113382Ethanol, 2-(ethylphenylamino)-, 1-acetate

Conditions

Temperature
60 °C

Procedure

A mixture of 49.6 g (300 mmol) of 15 and 50 ml of acetic acid anhydride in a 250 ml-flask, equipped with a CaCl2-tube is stirred overnight at 60° C. Then, the volatile compounds are evaporated and the crude product is distilled under vacuüm.

Workup

  1. customequipped with a CaCl2-tube
  2. customThen, the volatile compounds are evaporated
  3. distillationthe crude product is distilled under vacuüm

Sources & evidence

ORD record
ord-6df60bb41a4a44109ff4a456fc72be8e
Source dataset
uspto-grants-2005_03
Patent number
US06864347B2

Reaction notes

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