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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 983761Generated: October 31, 2026

Glutathione → Formaldehyde

https://huagongshe.com/reaction/983761

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGlutathioneHCID 124886—
Reactant5-({1-[(Carboxymethyl)imino]-3-(formylsulfanyl)-1-hydroxypropan-2-yl}imino)-5-hydroxynorvalineHCID 189122—
ReactantL-γ-Glutamyl-S-(hydroxymethyl)-L-cysteinylglycineHCID 447123—
ProductFormaldehydeHCID 712—
ProductGlutathioneHCID 124886—

Reaction Steps

To be exact, the glutathione-dependent formaldehyde dehydrogenase (EC 1.2.1.1) used in the present invention is an enzyme reversibly catalyzes the production of S-formylglutathione and reduced coenzyme in the presence of oxidized coenzyme, using, as a substrate, S-hydroxylmethylglutathione non-enzymatically produced from glutathione and formaldehyde.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06867012B2
Source datasetuspto-grants-2005_03
ORD IDord-8ef0eaa61b114f37aee8bae76f46fbea
Source noteuspto-grants-2005_03