Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 983861Generated: October 26, 2026

2,4-Dichlorobenzylidenemalononitrile → 5-Aminomethyl-6-(2,4-dichloro-phenyl)-2-naphthalen-1-yl-pyrimidin-4-ylamine

https://huagongshe.com/reaction/983861

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DichlorobenzylidenemalononitrileHCID 18089—
ReactantNaphthalene-1-carboxamidineHCID 12301251—
Product5-Aminomethyl-6-(2,4-dichloro-phenyl)-2-naphthalen-1-yl-pyrimidin-4-ylamineHCID 10172894—

Reaction Steps

The title compound, MS: m/e=395.3 (M+H+), was prepared from naphthalene-1-carboxamidine and 2-(2,4-dichloro-benzylidene)-malononitrile in analogy to the process described in Example 11 as a solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06867205B2
Source datasetuspto-grants-2005_03
ORD IDord-e215e16c692c4a35b04a5886e11de604
Source noteuspto-grants-2005_03