HCID 10268826, compound → HCID 9814705, compound

Participants

Reaction Steps

5-(4-Fluorophenyl)-6-(4-pyridyl)-2,3-dihydropyrrolo-[2,1-b]-thiazole-7-carboxylic acid (example 11, 120 mg, 0.35 mmol) is heated under argon in an oil bath firstly at 140° C. for 2 h and then at 180° C. for 3 h. After cooling to RT, the brown-red melt cake is digested with a little EtOH. The undissolved, red-brown substance is filtered off with suction, washed with ether and dried: 0.07 g.

Provenance & Evidence