HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 983913Generated: October 29, 2026
Proline benzyl ester hydrochloride → HCID 22557512, compound
https://huagongshe.com/reaction/983913
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Proline benzyl ester hydrochloride | HCID 2733413 | — |
| Reactant | Isonicotinoyl chloride hydrochloride | HCID 12262826 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 22557512 | HCID 22557512 | — |
Reaction Steps
L-Proline benzyl ester hydrochloride (2.42 g, 0.01 mol) dissolved in pyridine (80 ml) is treated in portions at 3° C. (ice-bath cooling) with isonicotinoyl chloride hydrochloride (1.78 g, 0.01 mol), the IT increasing to 10° C. After removing the ice bath, the mixture is stirred for 5 h, the batch turning greenish.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06867211B2 |
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| Source dataset | uspto-grants-2005_03 |
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| ORD ID | ord-61c6918c0194461abb1f36475a58f8d8 |
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| Source note | uspto-grants-2005_03 |
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