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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 983997Generated: October 31, 2026

2-(6-fluoro-1H-indol-3-yl)acetamide → 3-(6-Fluoro-1H-indol-3-yl)-4-(4-hydroxylmethyl-5,6-dihydro-4H-pyrrolo[3,2, 1-ij]quinolin-1-yl)pyrrole-2,5-dione

https://huagongshe.com/reaction/983997

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(6-fluoro-1H-indol-3-yl)acetamideHCID 21950062—
Reactant(4-hydroxymethyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)oxoacetic acid methyl esterHCID 69742777—
Product3-(6-Fluoro-1H-indol-3-yl)-4-(4-hydroxylmethyl-5,6-dihydro-4H-pyrrolo[3,2, 1-ij]quinolin-1-yl)pyrrole-2,5-dioneHCID 22556861—

Reaction Steps

Beginning with 2-(6-fluoro-1H-indol-3-yl)acetamide and (4-hydroxymethyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)oxoacetic acid methyl ester, the title compound was prepared essentially as described in Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06867198B2
Source datasetuspto-grants-2005_03
ORD IDord-54271e7ed7b04dd192a7b6964aff59a2
Source noteuspto-grants-2005_03