HRID984003

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COC(=O)C(=O)c1c[nH]c2c(CO[Si](C(C)C)(C(C)C)C(C)C)cccc12

HCID69742759

未命名化合物

结构：CC(C)(C)OC(=O)C1Cn2ccc3c(CC(N)=O)ccc(c32)CN1

HCID69745709

未命名化合物

PRODUCTS

生成物

结构：CC(C)[Si](OCc1cccc2c(C3=C(c4ccc5c6c4ccn6CC(C(=O)OC(C)(C)C)NC5)C(=O)NC3=O)c[nH]c12)(C(C)C)C(C)C

HCID69743447

未命名化合物

PROCEDURE

实验过程

Beginning with 7-Carbamoylmethyl-3,4-dihydro-1H-[1,4]diaze-pino[6,7,1-hi]indole-2-carboxylic acid tert-butyl ester and oxo-(7-triisopropylsilanyloxymethyl-1H-indol-3-yl)-acetic acid methyl ester, the title compound was prepared essentially as described in Example 1.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-818a23efd95c43eba89a9cf316428ff5
来源数据集: uspto-grants-2005_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06867198B2
来源说明: uspto-grants-2005_03

反应 SMILES

[C:1]([O:5][C:6]([CH:8]1[NH:20][CH2:19][C:17]2=[C:18]3[C:13](=[C:14]([CH2:21][C:22](=[O:24])[NH2:23])[CH:15]=[CH:16]2)[CH:12]=[CH:11][N:10]3[CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].C[O:26][C:27](=O)[C:28](=O)[C:29]1[C:37]2[C:32](=[C:33]([CH2:38][O:39][Si:40]([CH:47]([CH3:49])[CH3:48])([CH:44]([CH3:46])[CH3:45])[CH:41]([CH3:43])[CH3:42])[CH:34]=[CH:35][CH:36]=2)[NH:31][CH:30]=1>>[C:1]([O:5][C:6]([CH:8]1[NH:20][CH2:19][C:17]2=[C:18]3[C:13](=[C:14]([C:21]4[C:22](=[O:24])[NH:23][C:27](=[O:26])[C:28]=4[C:29]4[C:37]5[C:32](=[C:33]([CH2:38][O:39][Si:40]([CH:41]([CH3:43])[CH3:42])([CH:47]([CH3:49])[CH3:48])[CH:44]([CH3:46])[CH3:45])[CH:34]=[CH:35][CH:36]=5)[NH:31][CH:30]=4)[CH:15]=[CH:16]2)[CH:12]=[CH:11][N:10]3[CH2:9]1)=[O:7])([CH3:4])([CH3:2])[CH3:3]